Don't miss the next webinar organised by the VPHi Young Scientists Committee scheduled for Wednesday 23 October 2024 at 11am CET: VPHi Best Thesis Award winner Sara Bridio from Politecnico di Milano will present her work on "In silico high-fidelity and surrogate models of the thrombectomy procedure" under the moderation of the students of the VPHi Young Scientists Committee.
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Abstract:
Acute ischemic stroke (AIS) is a pathology caused by an occlusion in a cerebral artery, which prevents the blood perfusion of brain tissues, and if not treated in a short time can cause severe neurological damage to the patient. Mechanical thrombectomy (MT) is a minimally-invasive treatment aiming at removing the occluding thrombus by means of a stent-retriever and/or aspiration catheters. MT has become the standard of care for AIS due to a large vessel occlusion, but the clinical outcomes still need to be improved. In my PhD, I developed in silico models of the MT procedure with stent-retriever, with different modelling approaches for different contexts of use. First, I developed a high-fidelity finite-element model that accurately replicates the clinical procedure, useful to study the causes of complications and to optimize the devices and the procedure. I then explored different surrogate modelling techniques to create predictive models of MT outcomes, with the aim of running the first in silico stroke trials and to create a tool for a fast patient-specific pre-operative planning.
Biosketch:
Sara Bridio got her PhD degree in Bioengineering cum laude at Politecnico di Milano (Italy) in 2023. She got her Master’s degree cum laude at Politecnico di Milano, with a specialization in Biomechanics and Biomaterials. She has been visiting researcher at Emory University (Atlanta, USA) in 2018 and at Universitat Politècnica de Catalunya (Barcelona, Spain) in 2022. Her research activity has been focused on computational modelling of cardiovascular pathologies and treatments. She is now a researcher at the European Commision’s Joint Research Centre (Ispra, Italy), continuing to deal with the use of computational modelling in biomedical research and clinical applications.
Sara received the Young Researcher Award at the 2022 European Solid Mechanics Conference, and the award for the Best Presentation in “Biomechanics in and for clinics” by the Italian Chapter of the European Society of Biomechanics in 2022. Her PhD thesis received the Best PhD Thesis Award by the VPH Institute and by the Italian Gruppo Nazionale di Bioingegneria.
This webinar is organised within the VPHi Keynote Webinar series, a quarterly event organized by the VPHi Young Scientists Committee that provides a forum for access to senior community members and their expert competence for chiefly young scientists, but also to the VPH community as a whole.
With the series, VPHi wishes to:
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You can propose names and topics by sending an email to student.committee@vph-institute.org
