VPHi Success Stories

An increasing number of digital technologies are reaching the patient, sometimes directly but more often through their physicians and through the devices/ drugs they are relying on. In this brochure the VPHi has collected a first selection of in silico medicine success stories that have brought a significant impact!

The use of computer modeling and simulation in healthcare is referred to by many names: digital twins in healthcare, in silico medicine or Virtual Physiological Human technologies. Whatever the label, the key concept is the use of computer modeling and simulation in prevention, diagnosis, therapy design and patient follow-up, across all organ systems and all therapeutic classes. 

In silico medicine has made significant progress over the last couple of years in many ways. Looking at in silico medicine as a scientific field, there is an increasing number of studies where in silico technologies were important to reach new biological insights or allow the translation to (pre)clinical studies. There is an increased uptake of in silico technologies within industry, both Medtech and Pharma, and there is a growing number of start-up companies exclusively providing in silico medicine services. Regulatory agencies are working with the in silico community to establish the appropriate regulatory framework for these technologies. 

Policy makers across the globe are increasingly aware of the benefits in silico medicine technologies and their potential impact on society. Specific activities are starting up with other stakeholders (medical professionals, patient organizations, health technology assessment agencies, payers) to identify needs and pitfalls for a further roll-out of in silico technologies across all aspects of the healthcare system.

In this brochure you will find six in silico medicine success stories:

  1. Predictive planning for structural heart interventions
  2. Respiratory healthcare by design
  3. Virtual Patients for medical education
  4. The Lung Physiome and virtual patient models
  5. Risk of sudden cardiac death: who and why? How computational techniques may improve patient care
  6. CT-based patient - specific model to predict the risk of hip fracture 

The applications range from the understanding of cause of medical problems over the design/testing of drugs and devices in virtual populations to teaching instruments for medical doctors, covering a variety of organ systems. This is just a first selection of success stories. If you want your story to be added to this selection, please contact us by sending an email to: manager@vph-institute.org.

Download the brochure here


Date: 01/12/2020 | Tag: | News: 1149 of 1626
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